An efficient virus-induced gene silencing
Clem
June 13, 2021
Gene-Modifying Applied sciences Paired With Viral Vectors for Translational Analysis Into Neurodegenerative Ailments
Ailments of the central nervous system (CNS) have traditionally been among the many most troublesome to deal with utilizing typical pharmacological approaches. This is because of a confluence of things, together with the restricted regenerative capability and general complexity of the mind, issues related to repeated drug administration, and difficulties delivering medication throughout the blood-brain barrier (BBB). Viral-mediated gene switch represents a pretty various for the supply of therapeutic cargo to the nervous system. Crucially, it often requires solely a single injection, whether or not that be a gene substitute technique for an inherited dysfunction or the supply of a genome- or epigenome-modifying assemble for remedy of CNS illnesses and issues.
It’s thus comprehensible that appreciable effort has been put in direction of the event of improved vector techniques for gene switch into the CNS. Totally different viral vectors are in fact tailor-made to their particular purposes, however they typically ought to share a number of key properties. The best viral vector incorporates a high-packaging capability, environment friendly gene switch paired with sturdy and sustained expression, lack of oncogenicity, toxicity and pathogenicity, and scalable manufacturing for medical purposes. On this evaluation, we’ll dedicate consideration to viral vectors derived from human immunodeficiency virus sort 1 (lentiviral vectors; LVs) and adeno-associated virus (AAVs).
The excessive curiosity in these viral supply techniques vectors is because of: (i) sturdy supply and long-lasting expression; (ii) environment friendly transduction into postmitotic cells, together with the mind; (iii) low immunogenicity and toxicity; and (iv) compatibility with superior manufacturing strategies. Right here, we’ll define primary points of LV and AAV biology, notably specializing in approaches and strategies aiming to reinforce viral security.
We may also allocate a good portion of this evaluation to the event and use of LVs and AAVs for supply into the CNS, with a concentrate on the genome and epigenome-editing instruments primarily based on clustered repeatedly interspaced quick palindromic repeats/CRISPR-associated protein 9 (CRISPR/Cas 9) and the event of novel methods for the remedy of neurodegenerative illnesses (NDDs).
grdr
Anti-Human Galectin-1 Antibody |
102-PA131S |
ReliaTech |
100 µg |
EUR 126 |
Description: Galectin-1, also known as L14, BHL and galaptin, is a monomeric or homodimeric prototype galectin that is expressed in a variety of cells and tissues including muscle, heart, liver, prostate, lymph nodes, spleen, thymus, placenta, testis, retina, macrophages, B cells, T cells, dendritic cells, and tumor cells. It preferentially binds laminin, fibronectin, 90K/Mac2BP, CD45, CD43, CD7, CD2, CD3, and ganglioside GM1. Galectin-1 modulates cell growth and proliferation, either positively or negatively, depending on the cell type and activation status. It controls cell survival by inducing apoptosis of activated T cells and immature thymocytes. It modulates cytokine secretion by inducing Th2 type cytokines and inhibiting proinflammatory cytokine production. Galectin1 can also modulate cel-lcell as well as cell-lmatrix interactions and depending on the cell type and developmental stage, promote cell attachment or detachment. Galectin-1 has immunosuppressive and antiinflammatory properties and has been shown to suppress acute and chronic inflammation and autoimmunity. Human and mouse galectin1 share about 88% amino acid sequence similarity. |
Anti- Galectin-1 Antibody |
GWB-6F6392 |
GenWay Biotech |
0.1 mg |
Ask for price |
anti- Galectin-1 antibody |
FNab03314 |
FN Test |
100µg |
EUR 606.3 |
|
Description: Antibody raised against Galectin-1 |
anti- Galectin-1 antibody |
FNab03315 |
FN Test |
100µg |
EUR 658.5 |
|
Description: Antibody raised against Galectin-1 |
Human Galectin-1 (Gal-1) Antibody |
30005-05111 |
AssayPro |
150 ug |
EUR 215 |
Human Galectin-1 (LGALS1) |
1-CSB-EP012882HU |
Cusabio |
-
Ask for price
-
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- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
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Description: Recombinant Human Galectin-1(LGALS1) expressed in E.coli |
Human Galectin-1 (LGALS1) |
1-CSB-EP012882HUb1 |
Cusabio |
-
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-
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-
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-
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-
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|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
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Description: Recombinant Human Galectin-1(LGALS1) expressed in E.coli |
human anti-human galectin-3 mAb(2D) |
E4A09H10-2D |
EnoGene |
50ug |
EUR 275 |
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
human anti-human galectin-3 mAb(5F) |
E4A09H10-5F |
EnoGene |
50ug |
EUR 275 |
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
human anti-human galectin-3 mAb(A5) |
E4A09H10-A5 |
EnoGene |
50ug |
EUR 275 |
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
human anti-human galectin-3 mAb(G2) |
E4A09H10-G2 |
EnoGene |
50ug |
EUR 275 |
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
human anti-human galectin-3 mAb(H3) |
E4A09H10-H3 |
EnoGene |
50ug |
EUR 275 |
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
human anti-human galectin-3 mAb(T1) |
E4A09H10-T1 |
EnoGene |
50ug |
EUR 275 |
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
human anti-human galectin-3 mAb(N13) |
E4A09H10-N13 |
EnoGene |
50ug |
EUR 275 |
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
Anti Human Galectin-3 Polyclonal Antibody |
KH040 |
Sceti |
each |
EUR 778.8 |
Description: The Anti Human Galectin-3 Polyclonal Antibody is available in Europe and for worldwide shipping via Gentaur. |
Recombinant Human Galectin-1 |
7-00427 |
CHI Scientific |
10µg |
Ask for price |
Recombinant Human Galectin-1 |
7-00428 |
CHI Scientific |
50µg |
Ask for price |
Recombinant Human Galectin-1 |
AP60482 |
SAB |
100ug |
EUR 449 |
|
Recombinant Human Galectin-1 |
HEOPP-0710 |
Cyagen |
10ug |
Ask for price |
RECOMBINANT HUMAN GALECTIN-1 |
GWB-BEA2B0 |
GenWay Biotech |
0.05 mg |
Ask for price |
Recombinant Human Galectin-1 |
cyt-544-10g |
ProSpec Tany |
10µg |
EUR 60 |
Recombinant Human Galectin-1 |
cyt-544-1mg |
ProSpec Tany |
1mg |
EUR 1350 |
Recombinant Human Galectin-1 |
cyt-544-50g |
ProSpec Tany |
50µg |
EUR 145 |
Human Galectin 1 Protein |
20-abx066725 |
Abbexa |
-
Ask for price
-
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-
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-
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-
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|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
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Human Galectin-1 Antibody Pair Set |
ABPR-ZB244 |
Creative Diagnostics |
5 plates, 15 plates |
Ask for price |
Description: Quantitative determination of Human Galectin-1 |
Galectin-1, human recombinant |
4648-10 |
Biovision |
each |
EUR 170.4 |
Galectin-1, human recombinant |
4648-1000 |
Biovision |
each |
EUR 1977.6 |
Galectin-1, human recombinant |
4648-50 |
Biovision |
each |
EUR 314.4 |
Galectin-1 Human Recombinant |
rAP-2252 |
Angio Proteomie |
Inquiry |
Ask for price |
Human Galectin-1 ELISA Kit |
EK5323 |
SAB |
96 tests |
EUR 599 |
|
Human Galectin-1 ELISA Kit |
IHULGALS1KT |
Innovative research |
each |
EUR 702 |
|
Description: Human Galectin-1 ELISA Kit |
Mouse Monoclonal anti-human Galectin-1 |
hAP-1228 |
Angio Proteomie |
50ug |
EUR 400 |
Sheep Polyclonal anti-Human Galectin-1 |
hAP-5905 |
Angio Proteomie |
50ug |
EUR 400 |
Anti-Mouse Galectin-1 Antibody |
103-M223 |
ReliaTech |
100 µg |
EUR 399 |
Description: The galectins constitute a large family of carbohydrate-binding proteins that function in many systems both intracellularly and following secretion. Galectins contain either one or two carbohydrate recognition domains (CRR) which mediate recognition of N-acetyl-lactosamine-containing glycoproteins. Some galectins exist in multiple isoforms due to alternative splicing. Individual galectins differ in their tissue distribution and in their carbohydrate-binding specificities. |
Human Galectin-1 (LEG1) Protein |
abx690252-100g |
Abbexa |
100 µg |
EUR 837.5 |
Human Galectin-1 (LEG1) Protein |
abx690252-20g |
Abbexa |
20 µg |
EUR 350 |
Human Galectin-1 (LGALS1) Protein |
abx670211-50ug |
Abbexa |
50 ug |
EUR 661.2 |
|
Human Galectin 1 ELISA kit |
E01A4669 |
BlueGene |
96T |
EUR 700 |
Description: ELISA |
Human Galectin 1 ELISA kit |
E01G0038-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A sandwich ELISA for quantitative measurement of Human Galectin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Galectin 1 ELISA kit |
E01G0038-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A sandwich ELISA for quantitative measurement of Human Galectin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Galectin 1 ELISA kit |
E01G0038-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A sandwich ELISA for quantitative measurement of Human Galectin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Galectin 1 ELISA Kit |
IHUGAL1KT |
Innovative research |
each |
EUR 667 |
|
Description: Human Galectin 1 ELISA Kit |
Galectin-10, Human |
E34M155H |
EnoGene |
5 μg |
EUR 155 |
Galectin-12, Human |
E34M156H |
EnoGene |
5 μg |
EUR 155 |
Galectin-13, Human |
E34M157H |
EnoGene |
5 μg |
EUR 155 |
Galectin-14, Human |
E34M158H |
EnoGene |
5 μg |
EUR 155 |
Galectin-16, Human |
E34M159H |
EnoGene |
5 μg |
EUR 155 |
Galectin-2, Human |
E34M149H |
EnoGene |
5 μg |
EUR 155 |
Galectin-3, Human |
E34M150H |
EnoGene |
5 μg |
EUR 155 |
Galectin-4, Human |
E34M151H |
EnoGene |
5 μg |
EUR 155 |
Galectin-7, Human |
E34M152H |
EnoGene |
5 μg |
EUR 155 |
Galectin-8, Human |
E34M153H |
EnoGene |
5 μg |
EUR 155 |
Galectin-9, Human |
E34M154H |
EnoGene |
5 μg |
EUR 155 |
Anti-Human Galectin-3 Antibody |
101-M424 |
ReliaTech |
100 µg |
EUR 399 |
Description: The galectins constitute a large family of carbohydrate-binding proteins that function in many systems both intracellularly and following secretion. Galectins contain either one or two carbohydrate recognition domains (CRR) which mediate recognition of N-acetyl-lactosamine-containing glycoproteins. Some galectins exist in multiple isoforms due to alternative splicing. Individual galectins differ in their tissue distribution and in their carbohydrate-binding specificities. |
Anti-Human Galectin-4 Antibody |
101-M425 |
ReliaTech |
100 µg |
EUR 399 |
Description: Galectin-4 is a member of the subfamily of galectins composed of two carbohydrate recognition domains having similar peptide chains. The galectins are a family of beta-galactoside-binding proteins having a role in modulating cell-cell and cell-matrix interactions, which inhibits chronic inflammations, GVHD, and allergic responses. LGALS4 expression is limited to small intestine, colon, and rectum, and it is underexpressed in colorectal cancer. LGALS4 binds as an endogenous ligand to glycosphingolipids having 3-O-sulfated Gal residues and bind as well to cholesterol-3-sulfate. LGALS4 takes part in cell adhesion. LGALS4 plays a role in crosslinking the lateral cell membranes of the surface-lining epithelial cells, thus supporting epithelial integrity against mechanical stress exerted by the bowel lume. |
Anti-Human Galectin-8 Antibody |
101-M427 |
ReliaTech |
100 µg |
EUR 399 |
Description: LGALS8 is a prostate-specific antigen that is solely overexpressed in malignant tumors and thus is a supplementary specific identifier of malignancies. LGALS8 is part of the galectin gene family which facilitates both cell-cell and cell matrix interactions in a method parallel to the selectin subgroup of C-type lectins. |
Anti-Human Galectin-3 Antibody |
101-M747 |
ReliaTech |
100 µg |
EUR 399 |
Description: The galectins constitute a large family of carbohydrate-binding proteins that function in many systems both intracellularly and following secretion. Galectins contain either one or two carbohydrate recognition domains (CRR) which mediate recognition of N-acetyl-lactosamine-containing glycoproteins. Some galectins exist in multiple isoforms due to alternative splicing. Individual galectins differ in their tissue distribution and in their carbohydrate-binding specificities. |
Anti-Human Galectin-7 Antibody |
101-M748 |
ReliaTech |
100 µg |
EUR 399 |
Description: Galectin-7 is a protein that in humans is encoded by the LGALS7 gene. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell–cell and cell–matrix interactions. Differential and in situ hybridizations indicate that this lectin is specifically expressed in keratinocytes. It is expressed at all stages of epidermal differentiation (i.e., in basal and supra-basal layers). It is moderately repressed by retinoic acid. The protein was found mainly in stratified squamous epithelium. The antigen localized to basal keratinocytes, although it was also found, albeit at lower levels, in the supra-basal layers where it concentrated to areas of cell-to-cell contact. The cellular localization and it’s striking down-regulation in cultured keratinocytes imply a role in cell–cell and/or cell–matrix interactions necessary for normal growth control. |
Anti-Human Galectin-3 Antibody |
102-P228 |
ReliaTech |
100 µg |
EUR 245.7 |
Description: The galectins constitute a large family of carbohydrate-binding proteins that function in many systems both intracellularly and following secretion. Galectins contain either one or two carbohydrate recognition domains (CRR) which mediate recognition of N-acetyl-lactosamine-containing glycoproteins. Some galectins exist in multiple isoforms due to alternative splicing. Individual galectins differ in their tissue distribution and in their carbohydrate-binding specificities. |
anti-human Galectin-3 antibody |
10-2887 |
Fitzgerald |
250 ug |
EUR 410 |
|
Description: Purified anti-human Galectin-3 antibody |
Anti-human Galectin-3 antibody |
STJ15100163 |
St John's Laboratory |
250 µg |
EUR 403.2 |
Description: This monoclonal antibody is for studies of antigen expression in cells and tissue sections using immunocytochemistry and immunoprecipitation |
Recombinant Human Galectin-1(LGALS1) |
AP70493 |
SAB |
1mg |
EUR 1978 |
|
Recombinant Human Galectin-1 (LGALS1) |
CSB-EP012882HU |
Cusabio |
1598 mg |
Ask for price |
Recombinant Human Galectin-1 (LGALS1) |
CSB-EP012882HUb1 |
Cusabio |
1599 mg |
Ask for price |
Recombinant Human Galectin-1 (LGALS1) |
Z101845 |
ABM |
15 µg |
EUR 105 |
Description: Galectin-1 is a member of the galectin family, and binds B-galactosidase moieties on glycoproteins or glycolipids. Galectins are primarily involved in modulation of cell-cell and cell-matrix interactions. Galectin-1 acts as a negative regulator of immunity, promoting immune suppression and lessening the inflammatory response. Galectin-1 binds CD45, CD3 and CD4, resulting in the inhibition of CD45 phosphatase dependant dephosphorylation of lyn kinase, as well as a number of other immune related receptors. Due to its function as a negative regulator of the immune response, and role inducing apoptosis in activated Th1 and Th17 cells, it is commonly found upregulated around malignant tumours. It has also been implicated as having a role in the development of immune tolerance during pregnancy, and is highly expressed at the maternal-fetal interface. As a dimer it down-regulates neutrophils by inducing exposure of phosphatidylserine, thereby marking the cell for apoptosis. It shares approximately 88% and 90% sequence similarity with mouse and rat galectin-1, respectively. Recombinant Human Galectin-1 is a 14.9kDa protein. |
Recombinant Human Galectin-1 (LGALS1) |
Z101847 |
ABM |
100 µg |
EUR 270 |
Description: Galectin-1 is a member of the galectin family, and binds B-galactosidase moieties on glycoproteins or glycolipids. Galectins are primarily involved in modulation of cell-cell and cell-matrix interactions. Galectin-1 acts as a negative regulator of immunity, promoting immune suppression and lessening the inflammatory response. Galectin-1 binds CD45, CD3 and CD4, resulting in the inhibition of CD45 phosphatase dependant dephosphorylation of lyn kinase, as well as a number of other immune related receptors. Due to its function as a negative regulator of the immune response, and role inducing apoptosis in activated Th1 and Th17 cells, it is commonly found upregulated around malignant tumours. It has also been implicated as having a role in the development of immune tolerance during pregnancy, and is highly expressed at the maternal-fetal interface. As a dimer it down-regulates neutrophils by inducing exposure of phosphatidylserine, thereby marking the cell for apoptosis. It shares approximately 88% and 90% sequence similarity with mouse and rat galectin-1, respectively. Recombinant Human Galectin-1 is a 14.9kDa protein. |
Recombinant Human Galectin-1 (LGALS1) |
Z101849 |
ABM |
1.0 mg |
EUR 1135 |
Description: Galectin-1 is a member of the galectin family, and binds B-galactosidase moieties on glycoproteins or glycolipids. Galectins are primarily involved in modulation of cell-cell and cell-matrix interactions. Galectin-1 acts as a negative regulator of immunity, promoting immune suppression and lessening the inflammatory response. Galectin-1 binds CD45, CD3 and CD4, resulting in the inhibition of CD45 phosphatase dependant dephosphorylation of lyn kinase, as well as a number of other immune related receptors. Due to its function as a negative regulator of the immune response, and role inducing apoptosis in activated Th1 and Th17 cells, it is commonly found upregulated around malignant tumours. It has also been implicated as having a role in the development of immune tolerance during pregnancy, and is highly expressed at the maternal-fetal interface. As a dimer it down-regulates neutrophils by inducing exposure of phosphatidylserine, thereby marking the cell for apoptosis. It shares approximately 88% and 90% sequence similarity with mouse and rat galectin-1, respectively. Recombinant Human Galectin-1 is a 14.9kDa protein. |
Human Galectin-1 ELISA ELISA Kit |
E16HE0311 |
EnoGene |
96T |
EUR 1000 |
Human Galectin-1 Recombinant Protein |
100-175 |
ReliaTech |
50 µg |
EUR 196.35 |
Description: Lectins, of either plant or animal origin, are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with β-galactoside moieties. Galectin-1 is an animal lectin that has been shown to interact with CD3, CD4, and CD45. It induces apoptosis of activated T-cells and T-leukemia cell lines and inhibits the protein phosphatase activity of CD45. Recombinant human Galectin-1 is a 14.5 kDa protein containing 134 amino acid residues. |
Human Galectin-1 Recombinant Protein |
100-175S |
ReliaTech |
10 µg |
EUR 92.4 |
Description: Lectins, of either plant or animal origin, are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with β-galactoside moieties. Galectin-1 is an animal lectin that has been shown to interact with CD3, CD4, and CD45. It induces apoptosis of activated T-cells and T-leukemia cell lines and inhibits the protein phosphatase activity of CD45. Recombinant human Galectin-1 is a 14.5 kDa protein containing 134 amino acid residues. |
Human Galectin-1 Recombinant Protein |
400-015 |
ReliaTech |
50 µg |
EUR 126 |
Description: Lectins, of either plant or animal origin, are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with beta-galactoside moieties. Galectin-1 is an animal lectin that has been shown to interact with CD3, CD4, and CD45. It induces apoptosis of activated T-cells and T-leukemia cell lines and inhibits the protein phosphatase activity of CD45. Recombinant human Galectin-1 is a 14.5 kDa protein containing 134 amino acid residues. |
Recombinant Human Galectin-1 Protein |
E40KMP1041 |
EnoGene |
20ug |
EUR 495 |
Recombinant Human Galectin-1 Protein |
PROTP09382-1 |
BosterBio |
50ug |
EUR 380.4 |
Description: Lectins, of either plant or animal origin, are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with β-galactoside moieties. Galectin-1 is an animal lectin that has been shown to interact with CD3, CD4, and CD45. It induces apoptosis of activated T-cells and T-leukemia cell lines and inhibits the protein phosphatase activity of CD45. Recombinant human Galectin-1 is a 14.5 kDa protein containing 134 amino acid residues. |
Human Galectin 10 Antibody |
32652-05111 |
AssayPro |
150 ug |
EUR 215 |
Human Galectin 8 Antibody |
33159-05111 |
AssayPro |
150 ug |
EUR 215 |
Human Galectin 2 Antibody |
33165-05111 |
AssayPro |
150 ug |
EUR 215 |
Human Galectin 13 Antibody |
33175-05111 |
AssayPro |
150 ug |
EUR 215 |
Human Galectin 1 (LGALS1) Protein |
abx066725-100g |
Abbexa |
100 µg |
EUR 512.5 |
Human Galectin 1 (LGALS1) Protein |
abx066725-10g |
Abbexa |
10 µg |
EUR 212.5 |
Human Galectin 1 (LGALS1) Protein |
abx066725-50g |
Abbexa |
50 µg |
EUR 362.5 |
Human Galectin 1 (LGALS1) Protein |
abx670211-100g |
Abbexa |
100 µg |
EUR 450 |
Human Galectin-1(LGALS1) ELISA kit |
E01A4871 |
BlueGene |
96T |
EUR 700 |
Description: ELISA |
Human Galectin-1(LGALS1) ELISA kit |
E01G0448-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Human Galectin-1(LGALS1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Galectin-1(LGALS1) ELISA kit |
E01G0448-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Human Galectin-1(LGALS1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Galectin-1(LGALS1) ELISA kit |
E01G0448-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Human Galectin-1(LGALS1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Galectin-1 (LGALS1) ELISA Kit |
AE35699HU-48Tests |
Abebio |
48 Tests |
EUR 325 |
|
Description: Human (Homo sapiens) |
Human Galectin-1 (LGALS1) ELISA Kit |
AE35699HU-96Tests |
Abebio |
96 Tests |
EUR 610 |
|
Description: Human (Homo sapiens) |
Human Galectin-1(LGALS1) ELISA kit |
CSB-EL012882HU-24T |
Cusabio |
1 plate of 24 wells |
EUR 198 |
|
Description: Quantitativesandwich ELISA kit for measuring Human Galectin-1 (LGALS1) in samples from serum, plasma, tissue homogenates, cell lysates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
Human Galectin-1(LGALS1) ELISA kit |
1-CSB-EL012882HU |
Cusabio |
-
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-
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|
- 1 plate of 96 wells
- 10 plates of 96 wells each
- 5 plates of 96 wells each
|
|
Description: Quantitativesandwich ELISA kit for measuring Human Galectin-1(LGALS1) in samples from serum, plasma, tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
Human Galectin 1 (GAL1) CLIA Kit |
20-abx190336 |
Abbexa |
-
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-
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-
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|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
Human Galectin 1 (GAL1) CLIA Kit |
abx196676-96tests |
Abbexa |
96 tests |
EUR 990 |
|
Human Galectin 1 (GAL1)CLIA Kit |
SCA321Hu-10x96wellstestplate |
Cloud-Clone |
10x96-wells test plate |
EUR 6777.36 |
|
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Galectin 1 (GAL1) in serum, plasma and other biological fluids. |
Human Galectin 1 (GAL1)CLIA Kit |
SCA321Hu-1x48wellstestplate |
Cloud-Clone |
1x48-wells test plate |
EUR 663.31 |
|
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Galectin 1 (GAL1) in serum, plasma and other biological fluids. |
Human Galectin 1 (GAL1)CLIA Kit |
SCA321Hu-1x96wellstestplate |
Cloud-Clone |
1x96-wells test plate |
EUR 896.16 |
|
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Galectin 1 (GAL1) in serum, plasma and other biological fluids. |
Human Galectin 1 (GAL1)CLIA Kit |
SCA321Hu-5x96wellstestplate |
Cloud-Clone |
5x96-wells test plate |
EUR 3672.72 |
|
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Galectin 1 (GAL1) in serum, plasma and other biological fluids. |
Human Galectin 1 (GAL1) CLIA Kit |
4-SCA321Hu |
Cloud-Clone |
-
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-
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-
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|
- 10 plates of 96 wells
- 5 plates of 96 wells
- 1 plate of 96 wells
|
|
Description: Double-antibody Sandwich chemiluminescent immunoassay for detection of Human Galectin 1 (GAL1)Serum, plasma and other biological fluids |
Human Galectin-1 (Gal-1) Antibody (Biotin Conjugate) |
30005-05121 |
AssayPro |
150 ug |
EUR 315 |
Human GAL1 -Galectin 1 - CLIA Kit |
E-CL-H0704-24Tests |
Elabscience Biotech |
24 Tests |
EUR 180 |
|
Description: Sandwich |
Human GAL1 -Galectin 1 - CLIA Kit |
E-CL-H0704-48Tests |
Elabscience Biotech |
48 Tests |
EUR 546 |
|
Description: Sandwich |
Human GAL1 -Galectin 1 - CLIA Kit |
E-CL-H0704-96Tests |
Elabscience Biotech |
96 Tests |
EUR 682 |
|
Description: Sandwich |
Human GAL1 -Galectin 1 - CLIA Kit |
E-CL-H0704-96Tests10 |
Elabscience Biotech |
96 Tests *10 |
EUR 6820 |
|
Description: Sandwich |
Human GAL1 -Galectin 1 - CLIA Kit |
E-CL-H0704-96Tests5 |
Elabscience Biotech |
96 Tests *5 |
EUR 3410 |
|
Description: Sandwich |
Galectin-1 |
AP89417 |
SAB |
1mg |
EUR 2640 |
|
Galectin-1 |
AP84615 |
SAB |
1mg |
EUR 2640 |
|
Galectin-1 |
AP84729 |
SAB |
1mg |
EUR 2640 |
|
Galectin-1 |
AP84945 |
SAB |
1mg |
EUR 2640 |
|
Galectin-1 |
AP85083 |
SAB |
1mg |
EUR 2640 |
|
Human Galectin 1 (GAL1) ELISA kit |
201-12-3227 |
SunredBio |
96 tests |
EUR 528 |
|
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids. |
Human Galectin 1 (GAL1) ELISA Kit |
DLR-GAL1-Hu |
DL Develop |
96T |
EUR 422 |
|
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Human Galectin 1 (GAL1) ELISA Kit |
DLR-GAL1-Hu-48T |
DL Develop |
48T |
EUR 574.8 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Human Galectin 1 (GAL1) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Human Galectin 1 (GAL1) ELISA Kit |
DLR-GAL1-Hu-96T |
DL Develop |
96T |
EUR 745.2 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Human Galectin 1 (GAL1) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Human Galectin 1 (GAL1) ELISA Kit |
DL-GAL1-Hu |
DL Develop |
96T |
EUR 402 |
|
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Human Galectin 1 (GAL1) ELISA Kit |
EK14143 |
SAB |
96Т |
EUR 768 |
|
Human Galectin 1 ELISA Kit (GAL1) |
RK01436 |
Abclonal |
96 Tests |
EUR 625.2 |
Human Galectin 1 (GAL1) ELISA Kit |
RDR-GAL1-Hu-48T |
Reddot Biotech |
48T |
EUR 432.39 |
|
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. |
Human Galectin 1 (GAL1) ELISA Kit |
RDR-GAL1-Hu-48Tests |
Reddot Biotech |
48 Tests |
EUR 600 |
Human Galectin 1 (GAL1) ELISA Kit |
RDR-GAL1-Hu-96T |
Reddot Biotech |
96T |
EUR 617.72 |
|
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. |
Human Galectin 1 (GAL1) ELISA Kit |
RDR-GAL1-Hu-96Tests |
Reddot Biotech |
96 Tests |
EUR 830.4 |
Human Galectin 1 (GAL1) ELISA Kit |
RD-GAL1-Hu-48T |
Reddot Biotech |
48T |
EUR 411.8 |
|
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. |
Human Galectin 1 (GAL1) ELISA Kit |
RD-GAL1-Hu-48Tests |
Reddot Biotech |
48 Tests |
EUR 573.6 |
Human Galectin 1 (GAL1) ELISA Kit |
RD-GAL1-Hu-96T |
Reddot Biotech |
96T |
EUR 588.3 |
|
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. |
Human Galectin 1 (GAL1) ELISA Kit |
RD-GAL1-Hu-96Tests |
Reddot Biotech |
96 Tests |
EUR 794.4 |
Human Galectin 1 (GAL1) ELISA Kit |
SEA321Hu-10x96wellstestplate |
Cloud-Clone |
10x96-wells test plate |
EUR 4091.29 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Galectin 1 (GAL1) in serum, plasma, tissue homogenates and other biological fluids. |
Human Galectin 1 (GAL1) ELISA Kit |
SEA321Hu-1x48wellstestplate |
Cloud-Clone |
1x48-wells test plate |
EUR 442.1 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Galectin 1 (GAL1) in serum, plasma, tissue homogenates and other biological fluids. |
An environment friendly virus-induced gene silencing (VIGS) system for purposeful genomics in Brassicas utilizing a cabbage leaf curl virus (CaLCuV)-based vector
CaLCuV-based VIGS successfully works in cabbage and contributes to environment friendly purposeful genomics analysis in Brassica crop species. Virus-induced gene silencing (VIGS), a posttranscriptional gene silencing methodology, is an efficient approach for analysing the capabilities of genes in vegetation. Nevertheless, no VIGS vectors have been obtainable for Brassica oleracea till now. Right here, tobacco rattle virus (TRV), pTYs and cabbage leaf curl virus (CaLCuV) gene-silencing vectors (PCVA/PCVB) had been chosen to enhance the VIGS system in cabbage utilizing the phytoene desaturase (PDS) gene as an environment friendly visible indicator of VIGS. We efficiently silenced the expression of PDS and noticed photobleaching phenomena in cabbage in response to pTYs and CaLCuV, with the latter being simpler to function and cheaper.
The parameters doubtlessly affecting the silencing effectivity of VIGS by CaLCuV in cabbage, together with the focusing on fragment technique, inoculation methodology and incubation temperature, had been then in contrast. The optimized CaLCuV-based VIGS system includes the next: an roughly 500 bp insert sequence, an Agrobacterium OD600 of 1.0, use of the vacuum osmosis methodology utilized on the bud stage, and an incubation temperature of 22 °C.
Utilizing these parameters, we achieved a steady silencing effectivity of 65%. To additional take a look at the effectiveness of the system, we chosen the Mg-chelatase H subunit (ChlH) gene in cabbage and knocked down its expression, and we noticed yellow leaves, as anticipated. We efficiently utilized the CaLCuV-based VIGS system to 2 different consultant Brassica crop species, B. rapa and B. nigra, and thus expanded the appliance scope of this method. Our VIGS system described right here will contribute to environment friendly purposeful genomics analysis in Brassica crop species.
Ocular Gene Remedy with Adeno-associated Virus Vectors: Present Outlook for Sufferers and Researchers
On this “Perspective”, we talk about ocular gene remedy – the affected person’s perspective, the assorted methods of gene substitute and gene modifying, the place of adeno-associated virus vectors, routes of supply to the attention and the remaining query – “why does immunity proceed to restrict efficacy?” Via the coordinated efforts of sufferers, researchers, granting companies and business, and after a few years of pre-clinical research, biochemical, mobile, and animal fashions, we’re seeing medical trials emerge for a lot of beforehand untreatable heritable ocular issues.
The pathway to therapies has been led by the profitable remedy of the RPE65 type of Leber congenital amaurosis with LUXTURNA TM . In some instances, immune reactions to the vectors proceed to happen, limiting efficacy.
The underlying mechanisms of irritation require additional research, and new vectors have to be designed that restrict the triggers of immunity. Researchers finding out ocular gene therapies and clinicians enrolling sufferers in medical trials should acknowledge the present limitations of those therapies to correctly handle expectations and keep away from disappointment, however we imagine that gene therapies are effectively on their solution to profitable, widespread utilization to deal with heritable ocular issues.
EBV-miR-BART12 accelerates migration and invasion in EBV-associated most cancers cells by focusing on tubulin polymerization-promoting protein 1
Epstein-Barr virus (EBV) an infection results in cancers with an epithelial origin, akin to nasopharyngeal most cancers and gastric most cancers, in addition to a number of blood cell-based malignant tumors, akin to lymphoma. Apparently, EBV can also be the primary virus discovered to hold genes encoding miRNAs. EBV encodes 25 kinds of pre-miRNAs that are lastly processed into 44 mature miRNAs. Most EBV-encoded miRNAs had been discovered to be concerned within the prevalence and improvement of EBV-related tumors.
Nevertheless, the perform of EBV-miR-BART12 stays unclear. The findings of the present research revealed that EBV-miR-BART12 binds to the three’UTR area of Tubulin Polymerization-Selling Protein 1 (TPPP1) mRNA and downregulates TPPP1, thereby selling the invasion and migration of EBV-related cancers, akin to nasopharyngeal most cancers and gastric most cancers.
The mechanism underlying this course of was discovered to be the inhibition of TPPP1 by EBV-miRNA-BART12, which, in flip, inhibits the acetylation of α-tubulin, and promotes the dynamic meeting of microtubules, remodels the cytoskeleton, and enhances the acetylation of β-catenin. β-catenin prompts epithelial to mesenchymal transition (EMT).
These two processes synergistically promote the invasion and metastasis of tumor cells. To one of the best of our information, that is the primary research to disclose the function of EBV-miRNA-BART12 within the improvement of EBV-related tumors in addition to the mechanism underlying this course of, and suggests potential targets and methods for the remedy of EBV-related tumors.
Mouse Podoplanin ELISA kit |
E03P0082-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A sandwich ELISA for quantitative measurement of Mouse Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Podoplanin ELISA kit |
E03P0082-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A sandwich ELISA for quantitative measurement of Mouse Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Podoplanin ELISA kit |
E03P0082-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A sandwich ELISA for quantitative measurement of Mouse Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Podoplanin ELISA Kit |
IMSPDPNKT |
Innovative research |
each |
EUR 752 |
|
Description: Mouse Podoplanin ELISA Kit |
anti- Podoplanin antibody |
FNab06598 |
FN Test |
100µg |
EUR 702 |
|
Description: Antibody raised against Podoplanin |
anti- Podoplanin antibody |
FNab06599 |
FN Test |
100µg |
EUR 702 |
|
Description: Antibody raised against Podoplanin |
Mouse Monoclonal anti-Rat Podoplanin Antibody |
xAP-0897 |
Angio Proteomie |
100ug |
EUR 280 |
Mouse Podoplanin (PDPN) Protein |
20-abx650139 |
Abbexa |
-
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-
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-
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-
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|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Mouse Podoplanin (PDPN) Protein |
abx694266-10nmol |
Abbexa |
10 nmol |
EUR 700 |
Mouse Podoplanin (PDPN) Protein |
abx694266-5nmol |
Abbexa |
5 nmol |
EUR 462.5 |
Mouse Podoplanin (PDPN) Protein |
abx650139-100g |
Abbexa |
100 µg |
EUR 537.5 |
Mouse Podoplanin (PDPN) Protein |
abx650139-10g |
Abbexa |
10 µg |
EUR 212.5 |
Mouse Podoplanin (PDPN) Protein |
abx650139-50g |
Abbexa |
50 µg |
EUR 375 |
Mouse Podoplanin (PDPN) CLIA Kit |
20-abx493858 |
Abbexa |
-
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-
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-
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|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
Mouse Podoplanin (PDPN) ELISA Kit |
abx571749-96tests |
Abbexa |
96 tests |
EUR 943.2 |
|
Mouse Podoplanin (PDPN) ELISA Kit |
20-abx154564 |
Abbexa |
-
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-
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-
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|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
Mouse Podoplanin (PDPN) ELISA Kit |
DLR-PDPN-Mu |
DL Develop |
96T |
EUR 475 |
|
Description: tissue homogenates, cell lysates or other biological fluids. |
Mouse Podoplanin (PDPN) ELISA Kit |
DLR-PDPN-Mu-48T |
DL Develop |
48T |
EUR 632.4 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Podoplanin (PDPN) in samples from tissue homogenates, cell lysates or other biological fluids. |
Mouse Podoplanin (PDPN) ELISA Kit |
DLR-PDPN-Mu-96T |
DL Develop |
96T |
EUR 825.6 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Podoplanin (PDPN) in samples from tissue homogenates, cell lysates or other biological fluids. |
Mouse Podoplanin (PDPN) ELISA Kit |
DL-PDPN-Mu |
DL Develop |
96T |
EUR 453 |
|
Description: tissue homogenates, cell lysates or other biological fluids. |
Mouse Podoplanin (PDPN) ELISA Kit |
EK8596 |
SAB |
96Т |
EUR 799 |
|
Mouse Podoplanin (PDPN) ELISA Kit |
AE28131MO-48Tests |
Abebio |
48 Tests |
EUR 325 |
|
Description: Mouse (Mus musculus) |
Mouse Podoplanin (PDPN) ELISA Kit |
AE28131MO-96Tests |
Abebio |
96 Tests |
EUR 610 |
|
Description: Mouse (Mus musculus) |
Mouse Podoplanin (PDPN) ELISA Kit |
RK13459 |
Abclonal |
96T |
EUR 280 |
Mouse Podoplanin (PDPN) ELISA Kit |
RDR-PDPN-Mu-48T |
Reddot Biotech |
48T |
EUR 487.52 |
|
Description: tissue homogenates, cell lysates and other biological fluids. |
Mouse Podoplanin (PDPN) ELISA Kit |
RDR-PDPN-Mu-48Tests |
Reddot Biotech |
48 Tests |
EUR 668.4 |
Mouse Podoplanin (PDPN) ELISA Kit |
RDR-PDPN-Mu-96T |
Reddot Biotech |
96T |
EUR 696.47 |
|
Description: tissue homogenates, cell lysates and other biological fluids. |
Mouse Podoplanin (PDPN) ELISA Kit |
RDR-PDPN-Mu-96Tests |
Reddot Biotech |
96 Tests |
EUR 928.8 |
Mouse Podoplanin (PDPN) ELISA Kit |
RD-PDPN-Mu-48T |
Reddot Biotech |
48T |
EUR 464.3 |
|
Description: tissue homogenates, cell lysates and other biological fluids. |
Mouse Podoplanin (PDPN) ELISA Kit |
RD-PDPN-Mu-48Tests |
Reddot Biotech |
48 Tests |
EUR 639.6 |
Mouse Podoplanin (PDPN) ELISA Kit |
RD-PDPN-Mu-96T |
Reddot Biotech |
96T |
EUR 663.3 |
|
Description: tissue homogenates, cell lysates and other biological fluids. |
Mouse Podoplanin (PDPN) ELISA Kit |
RD-PDPN-Mu-96Tests |
Reddot Biotech |
96 Tests |
EUR 888 |
Mouse Podoplanin (PDPN) ELISA Kit |
SEC719Mu-10x96wellstestplate |
Cloud-Clone |
10x96-wells test plate |
EUR 5834.88 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Podoplanin (PDPN) in tissue homogenates, cell lysates and other biological fluids. |
Mouse Podoplanin (PDPN) ELISA Kit |
SEC719Mu-1x48wellstestplate |
Cloud-Clone |
1x48-wells test plate |
EUR 585.7 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Podoplanin (PDPN) in tissue homogenates, cell lysates and other biological fluids. |
Mouse Podoplanin (PDPN) ELISA Kit |
SEC719Mu-1x96wellstestplate |
Cloud-Clone |
1x96-wells test plate |
EUR 785.28 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Podoplanin (PDPN) in tissue homogenates, cell lysates and other biological fluids. |
Mouse Podoplanin (PDPN) ELISA Kit |
SEC719Mu-5x96wellstestplate |
Cloud-Clone |
5x96-wells test plate |
EUR 3173.76 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Podoplanin (PDPN) in tissue homogenates, cell lysates and other biological fluids. |
Mouse Podoplanin (PDPN) ELISA Kit |
4-SEC719Mu |
Cloud-Clone |
-
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-
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-
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|
- 10 plates of 96 wells
- 5 plates of 96 wells
- 1 plate of 96 wells
|
|
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Podoplanin (PDPN) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species. |
Mouse PDPN(Podoplanin) ELISA Kit |
ELK7080-48T |
ELK Biotech |
48T |
Ask for price |
|
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse PDPN. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse PDPN. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse PDPN, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse PDPN in the samples is then determined by comparing the OD of the samples to the standard curve. |
Mouse PDPN(Podoplanin) ELISA Kit |
ELK7080-96T |
ELK Biotech |
96T |
Ask for price |
|
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse PDPN. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse PDPN. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse PDPN, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse PDPN in the samples is then determined by comparing the OD of the samples to the standard curve. |
Mouse PDPN(Podoplanin) ELISA Kit |
RE2052M-48wells |
Reed Biotech |
48 wells |
EUR 116.55 |
|
Mouse PDPN(Podoplanin) ELISA Kit |
RE2052M-96wells |
Reed Biotech |
96 wells |
EUR 161.55 |
|
Mouse Pdpn / Podoplanin ELISA Kit |
E2095m |
EIAab |
96T |
EUR 776 |
Anti-Rat Podoplanin Antibody |
104-M40 |
ReliaTech |
100 µg |
EUR 189 |
Description: Podoplanin is a well-recognized lymphatic endothelium marker, which can be used to reliably distinguish lymphatic vessels from blood vessels. It was originally discovered in kidney podocytes. This mouse monoclonal antibody (IgG) against rat podoplanin works well for immunohistochemistry with formalin-fixed paraffin embedded sections. This antibody also can be used in FACS sorting. |
Anti- Podoplanin Human Antibody |
GWB-F131C7 |
GenWay Biotech |
0.2 mg |
Ask for price |
Podoplanin |
E8ER1915-23 |
EnoGene |
100ul |
EUR 275 |
Description: Available in various conjugation types. |
Podoplanin |
E8ET1703-61 |
EnoGene |
100ul |
EUR 275 |
Description: Available in various conjugation types. |
Podoplanin |
AP87543 |
SAB |
1mg |
EUR 2640 |
|
Podoplanin |
AP79286 |
SAB |
1mg |
EUR 2640 |
|
Podoplanin |
AP86601 |
SAB |
1mg |
EUR 2640 |
|
Podoplanin |
AP87092 |
SAB |
1mg |
EUR 2640 |
|
Podoplanin |
MO47016 |
Neuromics |
100 ul |
EUR 418.8 |
Recombinant Mouse Podoplanin (C-Fc) |
CU73-10ug |
Novoprotein |
10ug |
EUR 157.2 |
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
Recombinant Mouse Podoplanin (C-Fc) |
CU73-1mg |
Novoprotein |
1mg |
EUR 2008.8 |
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
Recombinant Mouse Podoplanin (C-Fc) |
CU73-500ug |
Novoprotein |
500ug |
EUR 1399.2 |
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
Recombinant Mouse Podoplanin (C-Fc) |
CU73-50ug |
Novoprotein |
50ug |
EUR 327.6 |
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
Mouse Podoplanin, PDPN GENLISA ELISA |
KLM1437 |
Krishgen |
1 x 96 wells |
EUR 341 |
Anti-Human Podoplanin Antibody |
101-M40-FITC |
ReliaTech |
50 µg |
Ask for price |
Description: Podoplanin, also known as glycoprotein 36 (gp36), PA2.26 antigen, T1alpha (T1A), and aggrus, is a 36 kDa type I transmembrane sialoglycoprotein and member of the Podoplanin family. Podoplanin has three potential splice variants, the longest of which is represented by a 238 amino acid (aa) precursor (NP_006465). It contains an undefined signal sequence, a 22 aa transmembrane segment (aa 207228) and a short cytoplasmic tail (aa 229-238). The ECD contains abundant Ser/Thr residues that could serve as potential Olinked glycosolation sites. The cytoplasmic tail contains putative sites for protein kinase C phosphorylation. There are two potential alternate start sites at Met 77 (Swiss Prot #: Q86YL7) and Met 119 (EAW51692) that generate short forms. The 162 aa short form Podoplanin precursor shares 47% aa identity with mouse Podoplanin. Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells, and numerous tumors, including colorectal tumors, squamous cell carcinomas, testicular seminoma, and brain tumors. One study shows high expression of Podoplanin mRNA in placenta, lung, skeletal muscle, and heart, and weaker levels in brain, kidney, and liver. Podoplanin is the ligand for Ctype lectin-like receptor 2 (CLEC2). Their association is dependent on sialic acid on Oglycans of Podoplanin. Through its association with CLEC2, Podoplanin-induces platelet aggregation and tumor metastasis. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth. |
Anti-Human Podoplanin Antibody |
101-M40-PE |
ReliaTech |
50 µg |
Ask for price |
Description: Podoplanin, also known as glycoprotein 36 (gp36), PA2.26 antigen, T1alpha (T1A), and aggrus, is a 36 kDa type I transmembrane sialoglycoprotein and member of the Podoplanin family. Podoplanin has three potential splice variants, the longest of which is represented by a 238 amino acid (aa) precursor (NP_006465). It contains an undefined signal sequence, a 22 aa transmembrane segment (aa 207228) and a short cytoplasmic tail (aa 229-238). The ECD contains abundant Ser/Thr residues that could serve as potential Olinked glycosolation sites. The cytoplasmic tail contains putative sites for protein kinase C phosphorylation. There are two potential alternate start sites at Met 77 (Swiss Prot #: Q86YL7) and Met 119 (EAW51692) that generate short forms. The 162 aa short form Podoplanin precursor shares 47% aa identity with mouse Podoplanin. Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells, and numerous tumors, including colorectal tumors, squamous cell carcinomas, testicular seminoma, and brain tumors. One study shows high expression of Podoplanin mRNA in placenta, lung, skeletal muscle, and heart, and weaker levels in brain, kidney, and liver. Podoplanin is the ligand for Ctype lectin-like receptor 2 (CLEC2). Their association is dependent on sialic acid on Oglycans of Podoplanin. Through its association with CLEC2, Podoplanin-induces platelet aggregation and tumor metastasis. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth. |
Anti-Human Podoplanin Antibody |
101-M40S-FITC |
ReliaTech |
25 µg |
Ask for price |
Description: Podoplanin, also known as glycoprotein 36 (gp36), PA2.26 antigen, T1alpha (T1A), and aggrus, is a 36 kDa type I transmembrane sialoglycoprotein and member of the Podoplanin family. Podoplanin has three potential splice variants, the longest of which is represented by a 238 amino acid (aa) precursor (NP_006465). It contains an undefined signal sequence, a 22 aa transmembrane segment (aa 207228) and a short cytoplasmic tail (aa 229-238). The ECD contains abundant Ser/Thr residues that could serve as potential Olinked glycosolation sites. The cytoplasmic tail contains putative sites for protein kinase C phosphorylation. There are two potential alternate start sites at Met 77 (Swiss Prot #: Q86YL7) and Met 119 (EAW51692) that generate short forms. The 162 aa short form Podoplanin precursor shares 47% aa identity with mouse Podoplanin. Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells, and numerous tumors, including colorectal tumors, squamous cell carcinomas, testicular seminoma, and brain tumors. One study shows high expression of Podoplanin mRNA in placenta, lung, skeletal muscle, and heart, and weaker levels in brain, kidney, and liver. Podoplanin is the ligand for Ctype lectin-like receptor 2 (CLEC2). Their association is dependent on sialic acid on Oglycans of Podoplanin. Through its association with CLEC2, Podoplanin-induces platelet aggregation and tumor metastasis. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth. |
Anti-Human Podoplanin Antibody |
101-M40S-PE |
ReliaTech |
25 µg |
Ask for price |
Description: Podoplanin, also known as glycoprotein 36 (gp36), PA2.26 antigen, T1alpha (T1A), and aggrus, is a 36 kDa type I transmembrane sialoglycoprotein and member of the Podoplanin family. Podoplanin has three potential splice variants, the longest of which is represented by a 238 amino acid (aa) precursor (NP_006465). It contains an undefined signal sequence, a 22 aa transmembrane segment (aa 207228) and a short cytoplasmic tail (aa 229-238). The ECD contains abundant Ser/Thr residues that could serve as potential Olinked glycosolation sites. The cytoplasmic tail contains putative sites for protein kinase C phosphorylation. There are two potential alternate start sites at Met 77 (Swiss Prot #: Q86YL7) and Met 119 (EAW51692) that generate short forms. The 162 aa short form Podoplanin precursor shares 47% aa identity with mouse Podoplanin. Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells, and numerous tumors, including colorectal tumors, squamous cell carcinomas, testicular seminoma, and brain tumors. One study shows high expression of Podoplanin mRNA in placenta, lung, skeletal muscle, and heart, and weaker levels in brain, kidney, and liver. Podoplanin is the ligand for Ctype lectin-like receptor 2 (CLEC2). Their association is dependent on sialic acid on Oglycans of Podoplanin. Through its association with CLEC2, Podoplanin-induces platelet aggregation and tumor metastasis. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth. |
Anti-Human Podoplanin Antibody |
101-M41 |
ReliaTech |
100 µg |
EUR 199.5 |
Description: Podoplanin, also known as glycoprotein 36 (gp36), PA2.26 antigen, T1alpha (T1A), and aggrus, is a 36 kDa type I transmembrane sialoglycoprotein and member of the Podoplanin family. Podoplanin has three potential splice variants, the longest of which is represented by a 238 amino acid (aa) precursor (NP_006465). It contains an undefined signal sequence, a 22 aa transmembrane segment (aa 207-228) and a short cytoplasmic tail (aa 229-238). The ECD contains abundant Ser/Thr residues that could serve as potential O-linked glycosolation sites. The cytoplasmic tail contains putative sites for protein kinase C phosphorylation. There are two potential alternate start sites at Met 77 (Swiss Prot #: Q86YL7) and Met 119 (EAW51692) that generate short forms. The 162 aa short form Podoplanin precursor shares 47% aa identity with mouse Podoplanin. Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells, and numerous tumors, including colorectal tumors, squamous cell carcinomas, testicular seminoma, and brain tumors. One study shows high expression of Podoplanin mRNA in placenta, lung, skeletal muscle, and heart, and weaker levels in brain, kidney, and liver. Podoplanin is the ligand for C-type lectin-like receptor 2 (CLEC2). Their association is dependent on sialic acid on O-glycans of Podoplanin. Through its association with CLEC2, Podoplanin-induces platelet aggregation and tumor metastasis. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth. |
Anti-Human Podoplanin Antibody |
102-PA40AG |
ReliaTech |
50 µg |
EUR 147 |
Description: Podoplanin, also known as glycoprotein 36 (gp36), PA2.26 antigen, T1alpha (T1A), and aggrus, is a 36 kDa type I transmembrane sialoglycoprotein and member of the Podoplanin family. Podoplanin has three potential splice variants, the longest of which is represented by a 238 amino acid (aa) precursor (NP_006465). It contains an undefined signal sequence, a 22 aa transmembrane segment (aa 207-228) and a short cytoplasmic tail (aa 229-238). The ECD contains abundant Ser/Thr residues that could serve as potential Olinked glycosolation sites. The cytoplasmic tail contains putative sites for protein kinase C phosphorylation. There are two potential alternate start sites at Met 77 (Swiss Prot #: Q86YL7) and Met 119 (EAW51692) that generate short forms. The 162 aa short form Podoplanin precursor shares 47% aa identity with mouse Podoplanin. Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells, and numerous tumors, including colorectal tumors, squamous cell carcinomas, testicular seminoma, and brain tumors. One study shows high expression of Podoplanin mRNA in placenta, lung, skeletal muscle, and heart, and weaker levels in brain, kidney, and liver (1). Podoplanin is the ligand for Ctype lectin-like receptor 2 (CLEC2). Their association is dependent on sialic acid on Oglycans of Podoplanin. Through its association with CLEC2, Podoplanin induces platelet aggregation and tumor metastasis. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth. |
Anti-Human Podoplanin Antibody |
102-PA40S |
ReliaTech |
100 µg |
EUR 126 |
Description: Podoplanin, also known as glycoprotein 36 (gp36), PA2.26 antigen, T1alpha (T1A), and aggrus, is a 36 kDa type I transmembrane sialoglycoprotein and member of the Podoplanin family. Podoplanin has three potential splice variants, the longest of which is represented by a 238 amino acid (aa) precursor (NP_006465). It contains an undefined signal sequence, a 22 aa transmembrane segment (aa 207-228) and a short cytoplasmic tail (aa 229-238). The ECD contains abundant Ser/Thr residues that could serve as potential O-linked glycosolation sites. The cytoplasmic tail contains putative sites for protein kinase C phosphorylation. There are two potential alternate start sites at Met 77 (Swiss Prot #: Q86YL7) and Met 119 (EAW51692) that generate short forms. The 162 aa short form Podoplanin precursor shares 47% aa identity with mouse Podoplanin. Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells, and numerous tumors, including colorectal tumors, squamous cell carcinomas, testicular seminoma, and brain tumors. One study shows high expression of Podoplanin mRNA in placenta, lung, skeletal muscle, and heart, and weaker levels in brain, kidney, and liver. Podoplanin is the ligand for C-type lectin-like receptor 2 (CLEC2). Their association is dependent on sialic acid on O-glycans of Podoplanin. Through its association with CLEC2, Podoplanin-induces platelet aggregation and tumor metastasis. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth. |
Hamster Monoclonal anti-mouse Podoplanin |
mAP-0062 |
Angio Proteomie |
100ug |
EUR 250 |
Podoplanin (PDPN) Polyclonal Antibody (Mouse) |
4-PAC719Mu01 |
Cloud-Clone |
-
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-
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|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
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Description: A Rabbit polyclonal antibody against Mouse Podoplanin (PDPN) |
ELISA kit for Mouse Podoplanin (PDPN) |
KTE70775-48T |
Abbkine |
48T |
EUR 398.4 |
|
Description: Quantitative sandwich ELISA for measuring Mouse Podoplanin (PDPN) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Mouse Podoplanin (PDPN) |
KTE70775-5platesof96wells |
Abbkine |
5 plates of 96 wells |
EUR 2538 |
|
Description: Quantitative sandwich ELISA for measuring Mouse Podoplanin (PDPN) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Mouse Podoplanin (PDPN) |
KTE70775-96T |
Abbkine |
96T |
EUR 646.8 |
|
Description: Quantitative sandwich ELISA for measuring Mouse Podoplanin (PDPN) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Mouse PDPN (Podoplanin) |
E-EL-M2409 |
Elabscience Biotech |
1 plate of 96 wells |
EUR 640.8 |
|
Description: A sandwich ELISA kit for quantitative measurement of Mouse PDPN (Podoplanin) in samples from Serum, Plasma, Cell supernatant |
ELISA kit for Mouse PDPN (Podoplanin) |
ELK7080 |
ELK Biotech |
1 plate of 96 wells |
EUR 518.4 |
|
Description: A sandwich ELISA kit for detection of Podoplanin from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
Podoplanin antibody |
10R-P133a |
Fitzgerald |
100 ug |
EUR 438 |
|
Description: Mouse monoclonal Podoplanin antibody |
Podoplanin antibody |
10R-P155a |
Fitzgerald |
100 ug |
EUR 468 |
|
Description: Hamster monoclonal Podoplanin antibody |
Podoplanin antibody |
10R-7662 |
Fitzgerald |
100 ug |
EUR 754.8 |
Description: Mouse monoclonal Podoplanin antibody |
Podoplanin antibody |
10R-7663 |
Fitzgerald |
100 ug |
EUR 754.8 |
Description: Hamster monoclonal Podoplanin antibody |
Podoplanin antibody |
10R-7664 |
Fitzgerald |
100 ug |
EUR 754.8 |
Description: Mouse monoclonal Podoplanin antibody |
Podoplanin Antibody |
49474 |
SAB |
100ul |
EUR 499 |
Podoplanin Antibody |
49474-100ul |
SAB |
100ul |
EUR 399.6 |
Podoplanin Antibody |
49474-50ul |
SAB |
50ul |
EUR 286.8 |
Podoplanin Antibody |
DF12456 |
Affbiotech |
200ul |
EUR 420 |
Podoplanin Antibody |
E38PA2500 |
EnoGene |
100ul |
EUR 225 |
Description: Available in various conjugation types. |
Podoplanin antibody |
70R-13952 |
Fitzgerald |
100 ug |
EUR 484 |
|
Description: Affinity purified Rabbit polyclonal Podoplanin antibody |
Podoplanin antibody |
70R-11540 |
Fitzgerald |
100 ug |
EUR 632.4 |
Description: Rabbit polyclonal Podoplanin antibody |
Podoplanin antibody |
70R-PR007 |
Fitzgerald |
100 ug |
EUR 524 |
|
Description: Affinity purified Rabbit polyclonal Podoplanin antibody |
Podoplanin antibody |
70R-6816 |
Fitzgerald |
50 ug |
EUR 467 |
|
Description: Rabbit polyclonal Podoplanin antibody raised against the N terminal of PDPN |
Podoplanin antibody |
70R-6817 |
Fitzgerald |
50 ug |
EUR 467 |
|
Description: Rabbit polyclonal Podoplanin antibody raised against the middle region of PDPN |
Podoplanin antibody |
70R-50819 |
Fitzgerald |
100 ul |
EUR 242 |
|
Description: Purified Polyclonal Podoplanin antibody |
Podoplanin Antibody |
P1051-01m |
SAB |
0.1m |
EUR 250.8 |
Podoplanin Antibody |
P1051-1ml |
SAB |
1ml |
EUR 1129.2 |
Podoplanin Antibody |
R33852-100UG |
NSJ Bioreagents |
100 ug |
EUR 339.15 |
|
Description: Additional name(s) for this target protein: PDPN; AGGRUS; GP36; GP40; Gp38; HT1A-1; OTS8; PA2.26 |
Anti-D2-40/Podoplanin antibody |
STJ190048 |
St John's Laboratory |
200 µl |
EUR 236.4 |
Description: Unconjugated Mouse monoclonal to D2-40/Podoplanin (7D1) |
Podoplanin (PDPN) Polyclonal Antibody (Mouse), PE |
4-PAC719Mu01-PE |
Cloud-Clone |
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|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Mouse Podoplanin (PDPN). This antibody is labeled with PE. |
Podoplanin (PDPN) Polyclonal Antibody (Mouse), APC |
4-PAC719Mu01-APC |
Cloud-Clone |
-
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-
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|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Mouse Podoplanin (PDPN). This antibody is labeled with APC. |
Podoplanin (PDPN) Polyclonal Antibody (Mouse), Cy3 |
4-PAC719Mu01-Cy3 |
Cloud-Clone |
-
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|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Mouse Podoplanin (PDPN). This antibody is labeled with Cy3. |
Podoplanin (PDPN) Polyclonal Antibody (Mouse), HRP |
4-PAC719Mu01-HRP |
Cloud-Clone |
-
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|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Mouse Podoplanin (PDPN). This antibody is labeled with HRP. |
Podoplanin Mouse Monoclonal Antibody (IHC Gold) |
E44H20290 |
EnoGene |
250ul |
EUR 655 |
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
Rat Monoclonal anti-Mouse Podoplanin Antibody |
xAP-0812 |
Angio Proteomie |
100ug |
EUR 280 |
Podoplanin (PDPN) Polyclonal Antibody (Mouse), FITC |
4-PAC719Mu01-FITC |
Cloud-Clone |
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|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Mouse Podoplanin (PDPN). This antibody is labeled with FITC. |
Mouse Anti-Human Podoplanin monoclonal antibody, clone JID761 |
CABT-L2919-100uL500uL |
Creative Diagnostics |
100 uL, 500 uL |
EUR 602.4 |
Mouse Anti-Human Podoplanin monoclonal antibody, clone JID761 |
CABT-L2919 |
Creative Diagnostics |
100 µl, 500 µl |
Ask for price |
|
Description: Mouse |
Mouse Podoplanin, soluble Recombinant Protein |
S01-M46 |
ReliaTech |
5 µg |
EUR 63 |
Description: Podoplanin, also known as glycoprotein 38 (gp38), PA2.26 antigen, T1alpha (T1A), and aggrus, is a 38 kDa type I transmembrane sialoglycoprotein and member of the podoplanin family. Podoplanin is synthesized as a 172 amino acid (aa) precursor with a 22 aa signal sequence, a 119 aa extracellular domain (ECD), a 21 aa transmembrane region, and a short, 10 aa cytoplasmic tail. The ECD contains abundant Ser/Thr residues as potential sites for Oglycosylation, and the cytoplasmic region contains putative sites for kinase C and cAMP phosphorylation. Mouse Podoplanin shares 77% and 46% aa sequence identity with rat and human Podoplanin, respectively. Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells, and on numerous tumors including colorectal tumors, squamous cell carcinomas, testicular seminoma, and brain tumors. One study shows high expression of Podoplanin mRNA in placenta, lung, skeletal muscle, and heart, and weaker levels in brain, kidney, and liver. Podoplanin is the ligand for Ctype lectin like receptor 2 (CLEC2). Their association is dependent on sialic acid on Oglycans of Podoplanin. Through its association with CLEC2, Podoplanin induces platelet aggregation and tumor metastasis. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth. |
Podoplanin (PDPN) Antibody |
20-abx129101 |
Abbexa |
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|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Podoplanin (PDPN) Antibody |
20-abx131102 |
Abbexa |
-
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|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
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Podoplanin (PDPN) Antibody |
20-abx123399 |
Abbexa |
-
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|
|
|
Podoplanin (PDPN) Antibody |
20-abx114559 |
Abbexa |
-
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-
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|
|
|
Podoplanin (PDPN) Antibody |
20-abx137407 |
Abbexa |
-
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-
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|
|
|
Podoplanin (PDPN) Antibody |
20-abx005408 |
Abbexa |
-
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|
- 100 ul
- 200 ul
- 20 ul
- 50 ul
|
|
Podoplanin (PDPN) Antibody |
20-abx008317 |
Abbexa |
-
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|
|
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Podoplanin (PDPN) Antibody |
20-abx211099 |
Abbexa |
-
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-
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|
|
|
Podoplanin (PDPN) Antibody |
abx236598-100ug |
Abbexa |
100 ug |
EUR 661.2 |
|
Podoplanin (PDPN) Antibody |
abx236599-100ug |
Abbexa |
100 ug |
EUR 661.2 |
|
Podoplanin (PDPN) Antibody |
20-abx174125 |
Abbexa |
-
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|
|
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Podoplanin (PDPN) Antibody |
20-abx174126 |
Abbexa |
-
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Podoplanin (PDPN) Antibody |
20-abx178065 |
Abbexa |
-
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-
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|
|
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Podoplanin (PDPN) Antibody |
20-abx178066 |
Abbexa |
-
Ask for price
-
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|
|
|
Podoplanin (PDPN) Antibody |
20-abx178067 |
Abbexa |
-
Ask for price
-
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|
|
|
Podoplanin (PDPN) Antibody |
abx433110-200ul |
Abbexa |
200 ul |
EUR 460.8 |
|
Podoplanin (PDPN) Antibody |
20-abx339428 |
Abbexa |
-
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Podoplanin Antibody gp36 |
R30481 |
NSJ Bioreagents |
100 ug |
EUR 356.15 |
|
Description: Podoplanin is a protein that in humans is encoded by the PDPN gene. This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The International radiation Hybrid mapping consortium mapped the gene to chromosome 1. It is a typical type I membrane glycoprotein, with an N-terminal signal sequence, a signal sequence cleavage site, a C-terminal hydrophobic stretch, and a short cytoplasmic tail. It has been described as a differentiation antigen and influenza-virus receptor, and a marker of lung injury. |
Podoplanin Antibody / gp36 |
R30760 |
NSJ Bioreagents |
100 ug |
EUR 356.15 |
|
Description: PDPN (Podoplanin), also called T1A, T1A2, GP36, OTS8 or AGGRUS, is a protein that in humans is encoded by the PDPN gene. This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The PDPN gene is mapped to chromosome 1 by the International radiation Hybrid mapping consortium. The physiological function of PDPN may be related to its mucin-type character. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Immunohistochemical analysis of PDPN in placenta, kidney, lung, and nasal polyps showed expression at the apical plasma membrane of vascular endothelial cells and in alveolar epithelial cells. Overexpression of rat PDPN in human and rodent endothelial cells promoted formation of elongated cell extensions and significantly increased endothelial cell adhesion, migration, and tube formation. Inhibition of PDPN expression by small interfering RNAs decreased cell adhesion in cultured human dermal lymphatic endothelial cells. |
Pdpn Antibody /Podoplanin |
RQ6390 |
NSJ Bioreagents |
100 ug |
EUR 356.15 |
|
Description: Podoplanin (PDPN) is a protein that in humans is encoded by the PDPN gene. This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The International radiation Hybrid mapping consortium mapped the T1A gene to chromosome 1. It has got 162 amino acid protein which is a typical type I membrane glycoprotein, with an N-terminal signal sequence, a signal sequence cleavage site, a C-terminal hydrophobic stretch, and a short cytoplasmic tail. Northern blot analysis detected a 1.2-kb T1A2 transcript only in lung. It has been described as a differentiation antigen and influenza-virus receptor, and a marker of lung injury. |
Podoplanin Antibody / gp36 |
V8695-100UG |
NSJ Bioreagents |
100 ug |
EUR 349.3 |
|
Description: It recognizes a muco-protein of 38-43kDa, which is identified as Podoplanin (PDPN). It localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endotheliumas well as lymphoangiomas,Kaposi sarcomas,and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas. |
Podoplanin Antibody / gp36 |
V8695-20UG |
NSJ Bioreagents |
20 ug |
EUR 153.3 |
|
Description: It recognizes a muco-protein of 38-43kDa, which is identified as Podoplanin (PDPN). It localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endotheliumas well as lymphoangiomas,Kaposi sarcomas,and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas. |
Podoplanin Antibody / gp36 |
V8695SAF-100UG |
NSJ Bioreagents |
100 ug |
EUR 349.3 |
|
Description: It recognizes a muco-protein of 38-43kDa, which is identified as Podoplanin (PDPN). It localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endotheliumas well as lymphoangiomas,Kaposi sarcomas,and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas. |
Podoplanin Antibody / gp36 |
V3404-100UG |
NSJ Bioreagents |
100 ug |
EUR 424.15 |
|
Description: Podoplanin (PDPN) is a muco-protein which localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endothelium as well as lymphoangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas. |
Podoplanin Antibody / gp36 |
V3404-20UG |
NSJ Bioreagents |
20 ug |
EUR 186.15 |
|
Description: Podoplanin (PDPN) is a muco-protein which localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endothelium as well as lymphoangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas. |
Podoplanin Antibody / gp36 |
V3404SAF-100UG |
NSJ Bioreagents |
100 ug |
EUR 424.15 |
|
Description: Podoplanin (PDPN) is a muco-protein which localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endothelium as well as lymphoangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas. |
Podoplanin (PDPN) Antibody |
abx005408-100l |
Abbexa |
100 µl |
EUR 175 |
Podoplanin (PDPN) Antibody |
abx114559-100l |
Abbexa |
100 µl |
EUR 612.5 |
Podoplanin (PDPN) Antibody |
abx129101-100l |
Abbexa |
100 µl |
EUR 275 |
Podoplanin (PDPN) Antibody |
abx129101-1ml |
Abbexa |
1 ml |
EUR 750 |
Podoplanin (PDPN) Antibody |
abx129101-200l |
Abbexa |
200 µl |
EUR 337.5 |